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HRAS — RAC1

Pathways - manually collected, often from reviews:

• BioCarta map kinase inactivation of smrt corepressor: RAS (HRAS) → RAC1 (modification, activates)
• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: RAC1/GDP complex (RAC1) → RAS family/GTP/Tiam1 complex (HRAS_KRAS_HRAS_KRAS_NRAS-TIAM1) (modification, collaborate)
  Yamauchi et al., Proc Natl Acad Sci U S A 2005
  Evidence: assay, other species
• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: RAS family/GTP/Tiam1 complex (HRAS_KRAS_HRAS_KRAS_NRAS-TIAM1) → RAC1/GTP complex (RAC1) (modification, activates) Yamauchi et al., Proc Natl Acad Sci U S A 2005
  Evidence: assay, other species
• WikiPathways p38 MAPK Signaling Pathway: HRAS → RAC1 (activation)

Text-mined interactions from Literome

Kim et al., Arch Pharm Res 2004 : Rac1 was prominently activated by H-ras in MCF10A cells
Genot et al., EMBO J 1996 : Expression of dominant negative N17Rac also prevents TCR and p21ras activation of NFAT, but without interfering with the ERK-2 pathway