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IGFBP7 — TP53
Text-mined interactions from Literome
Suzuki et al., Carcinogenesis 2010
(Adenocarcinoma...) :
Luciferase and chromatin immunoprecipitation assays in unmethylated cells revealed that
p53 induces expression of
IGFBP7 upon binding to a p53 response element within intron 1 of the gene ... Treating methylated CRC cell lines with 5-aza-2'-deoxycytidine restored
p53 induced
IGFBP7 expression
Kim et al., Nucleic Acids Res 2012
:
SET/TAF-Iß interacted with p53 and
repressed transcription of
p53 target genes ... Our findings provide new insights into the
regulation of stress induced
p53 activation by HAT inhibiting histone chaperone
SET/TAF-Iß