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Fong et al., J Lipid Res 1991 : A non-receptor pathway was supported by two lines of evidence : 1 ) the inhibition could be reproduced with a lipid extract, and 2 ) oxidized LDL also inhibited scavenger receptor negative THP-1 cell IL-1 beta mRNA expression
Huang et al., J Lipid Res 1997 : We have also demonstrated, using cycloheximide as a inhibitor of protein synthesis, that the marked increase in LDL-R protein observed in LDL-IC stimulated THP-1 cells resulted from de novo synthesis of LDL-R protein