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CSF1 — HRAS
Text-mined interactions from Literome
Heidaran et al., Oncogene 1992
:
Despite this significant difference, both PDGF-BB and
CSF-1 increased the activation of
p21ras , the extent of which correlated well with the mitogenic response induced by each growth factor in these cells
Yang et al., J Clin Invest 2006
(Bone Resorption...) :
M-CSF stimulated
p21(ras)-GTP and Akt phosphorylation was elevated in Nf1 ( +/- ) osteoclasts associated with gains of function in survival, proliferation, migration, adhesion, and lytic activity
Wilson et al., Biochem Biophys Res Commun 1998
:
In contrast,
CSF-1 stimulated
p21Ras activity was blocked by 8BrcAMP thus correlating with the inhibition of proliferation