Gene interactions and pathways from curated databases and text-mining

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CCDC50 — EGF

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CCDC50 → EGF (decreases) Olsen et al., Cell 2006*
    Evidence: We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database
  • OpenBEL Selventa BEL large corpus: CCDC50 → EGF (increases) Tashiro et al., J Biol Chem 2006*
    Evidence: Ymer is found to be phosphorylated at tyrosine 145 and 146 upon EGF stimulation,
  • OpenBEL Selventa BEL large corpus: CCDC50 → EGF (increases) Olsen et al., Cell 2006*
    Evidence: We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database