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CPOX — MMP2

Text-mined interactions from Literome

Spinella et al., Cancer Res 2007 (Melanoma...) : Moreover, COX-1/COX-2 inhibitors block ET-induced PGE ( 2 ) and VEGF secretion, matrix metalloproteinase ( MMP ) activation, and cell invasion, indicating that both enzymes function as downstream mediators of ET-induced invasive properties
Bhatt et al., American journal of translational research 2010 : Results of the present study suggest that MMP-2 and MMP-9 inhibition in presence of COX inhibitor prevents the development of experimental diabetic retinopathy in rats and can be a potential approach for the treatment