Gene interactions and pathways from curated databases and text-mining

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CISH — LEPR

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: LEPR — CISH (interaction, mapped from mint intact)
  • STRING interaction: CISH — LEPR (interaction, mapped from mint intact)

Text-mined interactions from Literome

Steinberg et al., Am J Physiol Endocrinol Metab 2004 : The mechanism ( s ) responsible for the development of skeletal muscle leptin resistance is unknown ; however, a role for increased suppressor of cytokine signaling-3 ( SOCS3 ) inhibition of the leptin receptor has been demonstrated in other rodent tissues
Nair et al., Am J Respir Cell Mol Biol 2008 : Leptin receptor expression and activation of STAT-3, Src kinase, Suppressor of Cytokine Signaling-3 ( SOCS-3 ), and COX were evaluated by Western blotting and PCR