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IL8 — MAP2K7

Text-mined interactions from Literome

Holtmann et al., Mol Cell Biol 1999 (MAP Kinase Signaling System) : Constitutively active MAP kinase kinase 7 (MKK7) , an activator of the stress activated protein kinase/c-Jun N-terminal kinase ( SAPK/JNK ) pathway, induced IL-8 synthesis and transcription from a minimal IL-8 promoter
Watanabe et al., J Invest Dermatol 2009 (Psoriasis) : Next, we confirmed that selective mitogen activated protein kinase kinase inhibitors significantly inhibited IL-17F induced IL-8 production
Yang et al., Microvasc Res 2009 (AIDS Dementia Complex) : Inhibitors of STAT1, mitogen activated protein kinase kinase ( MEK ) ( PD98059 ), and phosphatidyl inositol 3 kinase (PI3K) ( LY294002 ), blocked gp120 induced STAT1 activation and significantly diminished IL-8- , IL-6-, and gp120 induced monocyte adhesion and migration across in vitro BBB models