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ANG — CCND1
Text-mined interactions from Literome
Guillemot et al., J Biol Chem 2000
:
Using a pharmacological and a co-transfection approach, we found that p21(ras), Raf-1, phosphatidylinositol 3-kinase and also the catalytic activity of SHP-2 and its Src homology 2 domains are required for
cyclin D1 promoter/reporter gene
activation by
Ang II through the regulation of MAPK/ERK activity
Guillemot et al., J Biol Chem 2001
(MAP Kinase Signaling System) :
We recently reported that in these cells,
Ang II
induced cyclin D1 promoter activation and protein expression in a phosphatidylinositol 3-kinase (PI3K)-, SHP-2-, and mitogen activated protein kinase/extracellular signal regulated kinase ( MAPK/ERK ) -dependent manner ( Guillemot, L., Levy, A., Zhao, Z. J., Béréziat, G., and Rothhut, B. ( 2000 ) J. Biol. Chem. 275, 26349-26358 )
Kanda et al., Cancer Res 2005
:
Ang1 up-regulated the expression of
cyclin D1 in both of these cells