Amrani et al., Am J Physiol Lung Cell Mol Physiol 2003
:
Expression array analysis of 23 cell cycle related genes showed that IFN-gamma inhibited EGF induced increases in E2F-1 expression, whereas induction of c-myc, cyclin D2, Egr-1, and mdm2 were unaffected ... Induction of E2F-1 protein and Rb hyperphosphorylation after mitogen stimulation was also suppressed by IFN-gamma Tschickardt et al., Int J Cancer 1995
:
RB and a novel E2F-1 binding protein in MHC class II deficient B-cell lines and normal IFN-gamma induction of the class IL transactivator CIITA in class II non-inducible RB-defective tumor lines