Gene interactions and pathways from curated databases and text-mining

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EIF4EBP1 — IGF2

Text-mined interactions from Literome

Sneddon et al., Am J Physiol Endocrinol Metab 2001 : These novel findings indicate that clenbuterol induced muscle anabolism is potentially mediated, at least in part, by an IGF-II induced activation of 4E-BP1 and p70 ( S6k )
Cao et al., Science signaling 2009 : Loss of Galpha ( i1 ) and Galpha ( i3 ) severely impaired the activation of Akt and of p70 S6 kinase and 4E-BP1 , downstream targets of mTORC1, in response to EGF, heparin binding EGF-like growth factor, and transforming growth factor alpha, but not insulin, insulin-like growth factor , or platelet derived growth factor
Xu et al., J Biol Chem 1998 : In addition, we find that amino acids are necessary for insulin-like growth factor ( IGF-I ) to stimulate the phosphorylation of PHAS-I indicating that a requirement for amino acids may be essential for other beta-cell growth factors in addition to insulin and IGF-I to activate this signaling pathway