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MET — RAC1

Pathways - manually collected, often from reviews:

• Reactome Reaction: MET → RAC1 (indirect_complex) Vikis et al., Proc Natl Acad Sci U S A 2000*, Vikis et al., Genes Dev 2002*
• Reactome Reaction: MET → RAC1 (reaction) Vikis et al., Proc Natl Acad Sci U S A 2000*, Vikis et al., Genes Dev 2002*

Text-mined interactions from Literome

Lokuta et al., Proc Natl Acad Sci U S A 2003 : Further, both calpain inhibition and stimulation with IL-8 and formyl-Met-Leu-Phe ( fMLP ) induced an increase in Cdc42 and Rac activation
Nakaya et al., Dev Cell 2004 : By electroporating genes into chick presomitic mesenchymal cells, we demonstrate that Cdc42 and Rac1 play important and different roles in the MET that generates the vertebrate somites
Abella et al., J Cell Sci 2010 : Epithelial cells expressing Gab1DeltaNck ( Y407F ) exhibit decreased Met dependent Rac activation, fail to induce dorsal ruffles, and have impaired cell migration and epithelial remodelling