Gene interactions and pathways from curated databases and text-mining

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CLDN1 — IRF6

Text-mined interactions from Literome

Hou et al., Amino Acids 2012 (Weight Gain) : Moreover, NAC prevented the LPS induced decrease in claudin-1 and occludin expression in the jejunal and ileal mucosae
Zhou et al., Surgery 2013 : Here, GEF-H1 knockdown or ROCK inactivation both not only significantly inhibited LPS induced actin stress fiber formation, phosphorylation of myosin light chain, and myosin associated phosphatase type 1, but also suppressed LPS induced loss of occludin, claudin-1 , and vascular endothelial (VE)-cadherin in ECs, which suggested that LPS induced stress fiber formation and cell-cell junctions disruption were closely associated with GEF-H1/RhoA/ROCK signaling activation ... Here, GEF-H1 knockdown or ROCK inactivation both not only significantly inhibited LPS induced actin stress fiber formation, phosphorylation of myosin light chain, and myosin associated phosphatase type 1, but also suppressed LPS induced loss of occludin, claudin-1 , and vascular endothelial (VE)-cadherin in ECs, which suggested that LPS induced stress fiber formation and cell-cell junctions disruption were closely associated with GEF-H1/RhoA/ROCK signaling activation