Gene interactions and pathways from curated databases and text-mining

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EDN1 — GCG

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Tomita et al., J Clin Invest 1990 : The effects of endothelin on arginine vasopressin (AVP)-, parathyroid hormone-, glucagon- , calcitonin-, and isoproterenol dependent cAMP accumulation were studied ... On the other hand, endothelin had no inhibitory effect on AVP dependent cAMP accumulation in cTAL or mTAL, parathyroid hormone dependent cAMP accumulation in Gl and PCT, or glucagon- , calcitonin-, and isoprotereol dependent cAMP accumulation in OMCD
Zimmerman et al., Metabolism 1995 : Endothelin-1 decreases glucose, inhibits glucagon , and stimulates insulin release in the rat