Gene interactions and pathways from curated databases and text-mining

◀ Back to IL15

IL15 — IL18

Text-mined interactions from Literome

Strengell et al., J Immunol 2003 : We have previously shown that IL-15 and IL-21 induce the expression of IFN-gamma, T-bet, IL-12R beta 2, and IL-18R genes both in NK and T cells
Croy et al., J Reprod Immunol 2003 : Here, we review recent studies showing that IL-15 is the critical cytokine controlling uNK cell differentiation and that uNK cells are activated by either IL-12 or IL-18 and by other factors when both IL-12 and IL-18 are genetically absent from implantation sites
D'Agostino et al., Scand J Immunol 2004 (Leishmaniasis, Visceral) : Interleukin-15 , as interferon-gamma, induces the killing of Leishmania infantum in phorbol-myristate-acetate activated macrophages increasing interleukin-12
Takahashi et al., Antimicrob Agents Chemother 2005 : In addition, ciprofloxacin suppressed the interleukin-18 induced production of tumor necrosis factor alpha, gamma interferon, and interleukin-12 in peripheral blood mononuclear cells by inhibiting the expression of intercellular adhesion molecule 1, B7.1, B7.2, and CD40 on monocytes, and this effect could be reversed by the addition of indomethacin or NS398
Tada et al., Infect Immun 2005 : The stimulation of DCs with MDP and FK565 in combination with lipid A, poly ( I:C ), and CpG DNA, but not with Pam3CSSNA, synergistically induced interleukin-12 (IL-12) p70 and gamma interferon ( IFN-gamma ), but not IL-18 , in culture supernatants and induced IL-15 on the cell surface
Schierloh et al., Immunology 2005 (Tuberculosis, Pulmonary) : Mycobacterium tuberculosis reduced the number of intracellular adhesion molecule (ICAM)-1 ( + ) CD14 ( + ) cells, but in the presence of IL-15 , IL-18 and anti-IL-10 its expression was up-regulated
Verri et al., Eur J Immunol 2007 (Arthritis, Rheumatoid) : Consistent with this observation, IL-15 induced IL-18 production, and IL-15 or IL-18 injection induced the production of MIP-2, MIP-1alpha, TNF-alpha and LTB4
Marshall et al., J Immunol 2010 (Arenaviridae Infections) : IL-12, IL-15, IL-18 , and IFN-gamma were not individually required for sensitization to produce IFN-gamma, but IL-15 was required for upregulation of granzyme B