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IL6 — TEC
Text-mined interactions from Literome
Woltman et al., J Am Soc Nephrol 2000
:
The results, obtained by enzyme linked immunosorbent assay, indicate that simultaneous activation of
TEC with IL-17 and CD40L synergistically
enhances production of
IL-6 ( 2.1-fold higher than sum of single stimulations ) and the chemokines IL-8 ( 15-fold ) and RANTES ( 5.8-fold ) as demonstrated by statistical analysis ( P : < 0.05 ), whereas effects on MCP-1 ( 1.4-fold ) are additive
Zemans et al., Cell Immunol 2009
:
Furthermore, LPS induced actin polymerization as well as MCP-1, tumor necrosis factor-alpha,
interleukin-6 , and interleukin-1beta expression are
dependent on
Tec kinase activity
Takahashi-Tezuka et al., Oncogene 1997
:
Consistent with these,
IL-6 or IL-3
induced the association between
Tec and the p85 subunit of PI-3 kinase in mammalian cells