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IL6 — MSH2

Text-mined interactions from Literome

Lindberg et al., Neurotox Res 2005 : Neither IFN-gamma nor alpha-MSH affected the Abeta induced secretion of IL-6, but resulted in a dose dependent increase in basal IL-6 release ... Agouti, the endogenous antagonist of MCR1 and 4, further increased the alpha-MSH induced secretion of IL-6
Colombo et al., Shock 2007 (Inflammation...) : Bleomycin induced expression of proinflammatory and profibrotic factors ( interleukin 6 , tumor necrosis factor-alpha, transforming growth factor-beta1, and inducible nitric oxide synthase ) and chemokines ( chemokine [C-C motif] ligand 2 and chemokine [C-C motif] ligand 5 ) was likewise significantly reduced by NDP-alpha-MSH
Jun et al., J Mol Endocrinol 2010 : Specific inhibition of MC2R and MC5R expression with short interfering Mc2r and Mc5r RNAs significantly attenuated the alpha-MSH induced increase of intracellular cAMP and both the level of Il6 mRNA and secretion of IL6 in 3T3-L1 adipocytes ... Finally, when injected into mouse tail vein, alpha-MSH dramatically increased the Il6 transcript levels in epididymal fat pads
Minutoli et al., Endocrinology 2011 (Inflammation...) : NDP-a-MSH inhibited IL-6 and TNF-a expression, decreased histological damage, and increased neural efferent activity
Spaccapelo et al., Eur J Pharmacol 2013 (Brain Ischemia...) : NDP-a-MSH increased hippocampus dentate gyrus ( DG ) expression of Wnt-3A, ß-catenin, Sonic hedgehog (Shh), Zif268, interleukin-10 (IL-10) and doublecortin ( DCX ), as detected at days 3, 6 and 10 after the ischemic insult
Delgado et al., J Leukoc Biol 1998 : We tested effects of alpha-MSH ( 1-13 ), alpha-MSH ( 11-13 ), and ACTH ( 1-24 ) on production of tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6) , and nitric oxide ( NO ) in a cultured murine microglial cell line ( N9 ) stimulated with lipopolysaccharide (LPS) plus interferon gamma (IFN-gamma)
Huang et al., Am J Physiol 1998 (Fever) : Intraperitoneal alpha-MSH also suppressed the LPS induced rise in plasma IL-6 , ACTH, and corticosterone ( CS ) levels ... Intracerebroventricular injection of SHU-9119, a potent melanocortin-4 receptor (MC4-R)/MC3-R antagonist, completely blocked the antipyretic effect of intraperitoneal alpha-MSH during the first 4 h after LPS but had no effect on alpha-MSH induced suppression of LPS stimulated plasma IL-6 and CS levels