Gene interactions and pathways from curated databases and text-mining

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GIF — IL6

Text-mined interactions from Literome

Bleau et al., Br J Pharmacol 2000 (Inflammation) : Supporting the role of IL-6, incubation of H(INF) in the presence of IL-6 for 4 h reduced P450 content by 40 %
Hashimoto et al., Inflammation 1992 : IFN-gamma, however, when added in combination with either IL-1 or TNF, modulated the effects of these cytokines ; INF-gamma inhibited the PCA expression and enhanced the reduction of TM and the production of IL-6 , which were induced by either IL-1 or TNF
Gorospe et al., Endocrinology 1992 : In contrast, both basal and FSH stimulated IL-6 release could be significantly suppressed by interferon gamma (INF-gamma)
Andrade et al., Scand J Immunol 2008 : Moreover, 30 days after the last EtOH administration, lower IL-6 response to INF-gamma and impaired NO production were still observed in response to IFN-gamma/LPS stimuli, with the IL-6 response to IFN-gamma being restored by IFN-gamma/LPS stimuli
Lin et al., J Am Soc Nephrol 2012 (Diabetes Mellitus, Experimental...) : Silencing of TLR4 with small interfering RNA attenuated high glucose induced I?B/NF-?B activation, inhibited the downstream synthesis of IL-6 and CCL-2, and impaired the ability of conditioned media from high glucose treated proximal tubule cells to induce transmigration of mononuclear cells