Gene interactions and pathways from curated databases and text-mining

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BAX — TAT

Text-mined interactions from Literome

Macho et al., Oncogene 1999 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive...) : These pre-apoptotic events were associated with the cleavage of the caspase-3, while the expression of Bcl-2, Bcl-XL and Bax proteins was not affected by the presence of Tat
Guan et al., Neuroscience 2006 (Brain Injuries...) : At the same time, through inhibiting phosphorylation of Bcl-2 ( a cytosolic target of JNK ) and the release of Bax from Bcl-2/Bax dimers, Tat-JBD attenuated Bax translocation to mitochondria and the release of cytochrome c induced by ischemia/reperfusion
Jajoo et al., Neuroscience 2008 : Functionally, PTX-B reduced Tat induced Bax and caspase-3 proteins and reduced cell apoptosis