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RAF1 — XRCC5
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Schmitt et al., Mol Cell Biol 2001
:
Activation of
Rap1 by cAMP
induces the association of Rap1 with
Raf-1 and limits Ras dependent activation of ERK
Vossler et al., Cell 1997
:
Rap1 , activated by mutation or by the cAMP dependent protein kinase PKA, is a selective
activator of B-Raf and an inhibitor of
Raf-1
Hu et al., J Biol Chem 1997
:
However,
Rap1A , which has an identical effector domain to that of Ras, can not
activate Raf-1 and even antagonizes several Ras functions in vivo
Hu et al., J Biol Chem 1999
:
Effect of phosphorylation on activities of
Rap1A to interact with Raf-1 and to
suppress Ras dependent
Raf-1 activation