Geng et al., Am J Pathol 2011
(Cachexia) :
PGC-1a promotes nitric oxide antioxidant defenses and inhibits FOXO signaling against cardiac cachexia in mice
Chung et al., Biosci Rep 2013
:
We further demonstrated that FoxO6 represses the expression of PGC-1a via direct binding to an upstream A/T-rich element ( AAGATATCAAAACA, -2228-2215 ) in the PGC-1a promoter