◀ Back to IL6

CALML3 — IL6

Text-mined interactions from Literome

Osterberg et al., Shock 2006 (Disease Models, Animal...) : CLP + SC-236 attenuated IL-6 in plasma and in ascitic fluid and CLP + indomethacin augmented TNF-alpha in ascitic fluid compared with CLP at 6 h. CLP + SC-236 gave a lesser degree of mucosal damage compared with CLP alone or with indomethacin at 6 and 24 h ( P < 0.05 )
Deutschman et al., Crit Care Med 2006 (Cholestasis, Intrahepatic...) : CLP induced cholestasis, steatosis, and hepatocellular injury in interleukin-6 -/-, but not interleukin-6 +/+, mice
Overhaus et al., Shock 2009 (Disease Models, Animal...) : Cecal ligation and puncture and simultaneous HS + CLP caused significant inflammatory messenger RNA induction of IL-6 , iNOS, IL-10, and heme oxygenase 1 compared with control and HS, and these responses were significantly suppressed in HS + delayed CLP colonic muscularis extracts
Hu et al., J Immunol 2009 (Inflammation...) : In this respect, when mice were pretreated in vivo with anti-CD1d blocking Ab, we observed not only that this inhibited the systemic rise of IL-6 and IL-10 levels in septic mice and improved overall septic survival, but that the CLP induced changes in liver macrophage IL-6 and IL-10 expressions were inversely effected by this treatment
Fan et al., Immunology 2010 (Inflammation...) : CLP induced plasma interleukin (IL)-6 was significantly increased 25 +/- 12 fold and caecal myeloperoxidase (MPO) activity was increased 2.4 +/- 0.3 fold in beta-arrestin 2 ( -/- ) compared with WT mice
Zhang et al., Exp Toxicol Pathol 2011 (Disease Models, Animal...) : Moreover, AS inhibited CLP induced the activation of mitogen activated protein kinases ( MAPKs ) and nuclear factor-?B ( NF-?B ), the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) protein in lung tissues, and the production of serum tumor necrosis factor ( TNF-a ) and interleukin-6 (IL-6)
Sha et al., Shock 2011 (Sepsis) : Treatment with TAK-242 ( 10 mg/kg i.v. ) in combination with imipenem ( 1 mg/kg s.c. ) 1 h after CLP significantly increased the survival rates of mice from 17 % to 50 % ( P = 0.01 ) and suppressed CLP induced increases in serum levels of IL-1[beta ], IL-6 , IL-10, and macrophage inflammatory protein 2 by 64 %, 73 %, 79 %, and 81 %, respectively ( P = 0.025 )
Herzig et al., Shock 2012 (Bacteremia...) : However, CLP induced hypothermia and systemic interleukin 6 and CXCL10 production were significantly attenuated in TYK2-deficient mice
Li et al., Mediators Inflamm 2013 (Lung Injury...) : In addition, PD inhibited CLP induced serum tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) production, lung cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase isoform ( iNOS ) protein expressions and NF-?B activation
Jiang et al., J Ethnopharmacol 2013 (Sepsis) : XBJ significantly reduced the mortality rate, anal temperature and expression of TNF-a, IL-1ß and IL-6 induced by CLP