Gene interactions and pathways from curated databases and text-mining

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CDKN1A — TCHP

Text-mined interactions from Literome

North et al., Oncogene 2000 : We show here that WR1065 and the pro-drug WR2721 activate the p53 tumor suppressor protein and induce the expression of the cyclin dependent kinase inhibitor p21waf-1 in the breast cancer cell line MCF-7, and in the mouse fibroblast cell line balb/c 3T3
Koutsodontis et al., J Biol Chem 2001 (Carcinoma, Hepatocellular...) : Sp1 plays a critical role in the transcriptional activation of the human cyclin dependent kinase inhibitor p21 ( WAF1/Cip1 ) gene by the p53 tumor suppressor protein