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POLR2E — TAT
Text-mined interactions from Literome
Liu et al., Virology 1999
:
Human immunodeficiency virus type 1
Tat dependent activation of an arrested
RNA polymerase II elongation complex
Stevens et al., Med Res Rev 2006
:
The
Tat-TAR dependent phosphorylation of
RNA polymerase II plays an important role in transcriptional elongation as well as in other post-transcriptional events
Lau et al., Cell cycle (Georgetown, Tex.) 2009
:
Hexamethylene bis-acetamide inducible protein 1 ( HEXIM1 ) is an inhibitor of the positive transcription elongation factor b ( P-TEFb ), which controls
RNA polymerase II transcription and human immunodeficiency virus
Tat transactivation
Ernest et al., J Biol Chem 1978
:
The
RNA polymerase II inhibitor, alpha-amanitin, completely
blocked the dibutyryl cyclic AMP mediated increase in
tyrosine aminotransferase mRNA activity
Wu-Baer et al., Proc Natl Acad Sci U S A 1995
:
Specific binding of
RNA polymerase II to the human immunodeficiency virus trans activating region RNA is
regulated by cellular cofactors and
Tat
Mavankal et al., Proc Natl Acad Sci U S A 1996
:
These studies are consistent with the model that
RNA polymerase II is a cellular
target for
Tat resulting in Tat mediated increases in transcriptional elongation from the HIV long terminal repeat
Pagtakhan et al., Virology 1997
:
We suggest that these interactions, rather than direct
Tat/Sp1 binding,
result in highly processive
RNA polymerase II complexes and full-length viral transcripts