Gene interactions and pathways from curated databases and text-mining

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ACER1 — CA2

Text-mined interactions from Literome

Murase et al., J Reprod Dev 2004 : Ejaculated boar spermatozoa, stored with the Beltsville TS extender at 17 degrees C for up to 3 days, were washed and preincubated for 10 min with C2-ceramide, an analogue of endogenous ceramide, C2-dihydroceramide ( C2-DH-ceramide ), a negative control to C2-ceramide, or with ( 1S,2R ) -D-erythro-2- ( N-myristoylamino ) -1-phenyl-1-propanol ( D-erythro-MAPP ), an inhibitor of alkaline ceramidase , followed by incubation and stimulation with 3 mM Ca2+ and 0.3 microM A23187 ( Ca2+/A23187 ) at 37 degrees C in air in a water bath
Sun et al., J Invest Dermatol 2008 : We report that Ca2+ ( o ) markedly upregulates the human alkaline ceramidase 1 ( haCER1 ) in HEKs ; and its upregulation mediates the Ca2+ ( o ) -induced growth arrest and differentiation of HEKs