Gene interactions and pathways from curated databases and text-mining

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HDC — IL6

Text-mined interactions from Literome

Yamaguchi et al., Toxicology 2000 (Inflammation) : Induction of histidine decarboxylase , the histamine forming enzyme, in mice by interleukin-12
Lázár-Molnár et al., Eur J Clin Invest 2002 (Melanoma...) : IL-6 inhibited the proliferation of WM35 melanoma cells and increased significantly the expression of histidine decarboxylase as well as histamine production
Wu et al., Int Immunopharmacol 2004 : Histamine production via mast cell independent induction of histidine decarboxylase in response to lipopolysaccharide and interleukin-1
Hornyak et al., Vascul Pharmacol 2005 (Capillary Leak Syndrome...) : In addition, the systemic effect on serum cytokine levels showed that HDC only moderately lowered IL-2 induced IFN-gamma, IL-6 , IL-10, IL-18 and TNF-alpha
Endo et al., Br J Pharmacol 1995 : Effects of macrophage depletion on the induction of histidine decarboxylase by lipopolysaccharide, interleukin 1 and tumour necrosis factor