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HGS — STX12

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: STX12 — HGS (physical association, affinity chromatography technology) Sun et al., J Cell Biol 2003*
• MIPS CORUM SNARE complex (HGS, SNAP25, STX13): SNARE complex (HGS, SNAP25, STX13) complex (HGS-SNAP25-STX12) Yan et al., J Biol Chem 2004*
• IRef Corum Interaction: Complex of HGS-SNAP25-STX12 (association, far western blotting) Yan et al., J Biol Chem 2004*
• IRef Hprd Interaction: Complex of 17 proteins (in vivo) Sun et al., J Cell Biol 2003*

Text-mined interactions from Literome

Tsujimoto et al., J Biol Chem 2000 : The presence of syntaxin enhances the binding of Hrs-2 to SNAP-25
Sun et al., J Cell Biol 2003 : Hrs inhibited formation of the syntaxin 13-SNAP-25-VAMP2 complex by displacing VAMP2 from the complex
Bilan et al., Exp Cell Res 2008 : In LLC-PK1 cells transfected with CFTR and in Caco-2 cells endogenously expressing CFTR, we demonstrated that endosomal SNARE protein overexpression inhibits CFTR activity but not swelling- or calcium activated iodide efflux, indicating a specific effect upon CFTR activity