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HSPB1 — SPARC

Text-mined interactions from Literome

Sosa et al., Proteomics 2007 (Melanoma) : Immunoblotting of the secreted fraction of RNAi transfected melanoma cells confirmed that downregulation of SPARC expression promoted decreased levels of N-CAD and CLU and increased secretion of HSP27
McClung et al., Carcinogenesis 2012 (Brain Neoplasms...) : Wound and transwell migration assays and western blot analysis confirm our previous results and indicate that dAcidic reduces SPARC induced migration and p38 MAPK/HSP27 signaling and dEGF decreases SPARC induced migration and dramatically decreases the expression and phosphorylation of HSP27 but is poorly internalized
Alam et al., Neuro Oncol 2013 (Brain Neoplasms...) : PTEN suppresses SPARC induced pMAPKAPK2 and inhibits SPARC induced Ser78 HSP27 phosphorylation in glioma ... As PTEN completely suppresses SPARC induced migration, we proposed that PTEN must also interfere with SPARC induced HSP27 signaling ... Therefore, this study determined the effects of PTEN expression on SPARC induced expression and phosphorylation of HSP27 ... In contrast, PTEN inhibits SPARC induced increases in Ser78 HSP27 phosphorylation relative to total HSP27