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NOX5 — SERPINE1

Text-mined interactions from Literome

Collins-Underwood et al., Free Radic Biol Med 2008 : Pharmacologic and genetic inhibition of NADPH oxidase blocked the radiation mediated upregulation of intracellular ROS, activation of NFkappaB, and upregulation of ICAM-1 and PAI-1
Jaulmes et al., Thromb Res 2009 (MAP Kinase Signaling System) : The aim of the present study was to characterize the role of NADPH oxidase and in particular Nox4 in the regulation of PAI-1 expression in cultured Human Umbilical Venous Endothelial Cells ( HUVECs ) ... The NADPH oxidase inhibitors DPI and S 17834 as well as Nox4 silencing decreased PAI-1 synthesis in human cultured endothelial cells demonstrating the involvement of the constitutively active Nox4 containing NADPH oxidase in ROS mediated PAI-1 transcription via p38 MAPK pathways
Zhao et al., Free radical research 2011 : The results suggest that NOX is required for oLDL induced HSF1 or PAI-1 expression in MEF, which was supported by the up-regulation of NOX, LOX-1, HSF1 and PAI-1 in apoE-KO mice