Vairo et al., Mol Cell Biol 2000
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Bcl-2 retards cell cycle entry through p27 ( Kip1 ), pRB relative p130, and altered E2F regulation
Yew et al., J Cell Physiol 2001
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In vertebrates, the proper and timely duplication of the genome during S-phase relies on the coordinated activities of positive regulators such as CDK-cyclins and E2F , and negative regulators such as CDK inhibitors of the Cip/Kip and INK4 families