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CD83 — IL10
Text-mined interactions from Literome
Young et al., Clin Diagn Lab Immunol 2004
(Bifidobacteriales Infections) :
Whereas
CD83 expression was increased and
IL-10 production was
induced by Bifidobacterium bifidum, Bifidobacterium longum, and Bifidobacterium pseudocatenulatum, B. infantis failed to produce these effects
Kretschmer et al., PloS one 2007
(Calcium Signaling) :
The forced premature overexpression of
CD83 on the CD83Tg B cells
results in reduced calcium signaling, reduced Ig secretion and a reciprocally increased
IL-10 production upon in vitro activation
Chen et al., Proc Natl Acad Sci U S A 2011
:
Prostaglandin E2 ( PGE ( 2 ) ), but not
IL-10 or TGF-ß, was
up-regulated specifically by
CD83 in monocytes
Uhde et al., Int Immunol 2013
:
Transgenic over-expression of
CD83 on B cells
leads to a reduced response to BCR engagement but to an enhanced secretion of
IL-10 upon LPS stimulation