Gene interactions and pathways from curated databases and text-mining

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CD83 — IL10

Text-mined interactions from Literome

Young et al., Clin Diagn Lab Immunol 2004 (Bifidobacteriales Infections) : Whereas CD83 expression was increased and IL-10 production was induced by Bifidobacterium bifidum, Bifidobacterium longum, and Bifidobacterium pseudocatenulatum, B. infantis failed to produce these effects
Kretschmer et al., PloS one 2007 (Calcium Signaling) : The forced premature overexpression of CD83 on the CD83Tg B cells results in reduced calcium signaling, reduced Ig secretion and a reciprocally increased IL-10 production upon in vitro activation
Chen et al., Proc Natl Acad Sci U S A 2011 : Prostaglandin E2 ( PGE ( 2 ) ), but not IL-10 or TGF-ß, was up-regulated specifically by CD83 in monocytes
Uhde et al., Int Immunol 2013 : Transgenic over-expression of CD83 on B cells leads to a reduced response to BCR engagement but to an enhanced secretion of IL-10 upon LPS stimulation