◀ Back to NOTCH4

NODAL — NOTCH4

Text-mined interactions from Literome

Raya et al., Genes Dev 2003 (Situs Inversus) : Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos
Takeuchi et al., Proc Natl Acad Sci U S A 2007 : Notch mediated induction of Nodal at the vertebrate node is a critical step in initiating left-right ( LR ) asymmetry
Hardy et al., Cancer Res 2010 (Melanoma...) : Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype ... Surprisingly, Notch4 is specifically required for expression of Nodal in aggressive cells and plays a vital role both in the balance of cell growth and in the regulation of the aggressive phenotype ... In addition, Notch4 function in vasculogenic mimicry and anchorage independent growth in vitro is due in part to Notch4 regulation of Nodal