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TLR2 — TLR9

Text-mined interactions from Literome

An et al., Immunology 2002 : While inhibition of extracellular signal related kinase and NF-kappaB activation suppressed the up-regulation of the expression of TLR2, TLR4 and TLR9 mRNA, inhibition of p38 kinase prevented the up-regulation of TLR2 and TLR4 mRNA expression but enhanced the up-regulation of TLR9 expression
Chuang et al., Nat Immunol 2004 : Here we describe how a RING finger protein, Triad3A, acts as an E3 ubiquitin-protein ligase and enhances ubiquitination and proteolytic degradation of some TLRs. Triad3A overexpression promoted substantial degradation of TLR4 and TLR9 with a concomitant decrease in signaling, but did not affect TLR2 expression or signaling
Duez et al., Eur J Dermatol 2006 (Asthma...) : During the allergic reaction, TLR engagement on DC directs the polarization of the T cell response and, while TLR2 and TLR4 may favour both Th1 and Th2 responses, TLR9 induces the development of regulatory T cells
Wu et al., Int J Immunogenet 2008 : As an important member of TLRs, TLR1 is involved in the recognition of triacylated lipoproteins and mycobacterial products by binding to TLR2 to form a heterodimer
Aravalli et al., Journal of neuroinflammation 2008 (Histoplasmosis) : Furthermore, Yps3p induced TLR2 signaling was suppressed by vaccinia virus encoded TLR inhibitors
van de Veerdonk et al., Immunobiology 2008 (Candidiasis) : In conclusion, TLR9 is a pathogen-recognition receptor for C. albicans, and TLR9 is involved in the induction of cytokines in response to C. albicans
Regueiro et al., Infect Immun 2009 : We showed that Klebsiella induced TLR2 and TLR4 upregulation was dependent on TLR activation
So et al., Glia 2009 (Cardiovirus Infections) : More importantly, TLR3 was required for TMEV induced early TLR2 upregulation in primary astrocytes leading to the production of TLR2 dependent cytokines such as IL-6
Chamorro et al., J Immunol 2009 : TLR triggering on tolerogenic dendritic cells results in TLR2 up-regulation and a reduced proinflammatory immune program
Messlik et al., J Proteome Res 2009 (Chronic Disease...) : The aim of this study was to characterize the role of TLR2 or TLR4 deficiency in epithelial cell stress responses under noninflamed and inflamed conditions using TLR-deficient mice and TLR ( -/- ) cross bred IL-10-deficient mice as a model for genetically driven experimental colitis
González et al., Clinical and vaccine immunology : CVI 2010 : We demonstrated that TLR9 activation by F. nucleatum and TLR2 activation by both bacteria appear to be involved in HIV-1 reactivation ; however, TLR4 activation had no effect
Summers et al., Arthritis Rheum 2011 (Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis...) : TLR-2 induces Th17 CD4 cells while TLR-9 can also direct vasculitis, by directing Th1 autoimmunity
Stridh et al., Journal of neuroinflammation 2011 (Hypoxia-Ischemia, Brain) : In contrast, TLR-2 was constitutively expressed in the brain and TLR-2 deficiency reduced HI injury
Kim et al., FEMS Microbiol Lett 2012 (Inflammation) : L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of toll-like receptor (TLR) 2 , TLR4, and TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative regulator of TLR ... L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of toll-like receptor (TLR) 2, TLR4, and TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative regulator of TLR
Liu et al., J Immunol 2012 : Moreover, we previously reported that TLR2 signaling by Mycobacterium tuberculosis or other TLR2 agonists inhibited TLR9 induction of IFN-I and IFN-I dependent MHC-I Ag cross processing
Jia et al., Shanghai Kou Qiang Yi Xue 2011 : CD14, TLR4 receptors are involved in P.e-LPS effect and CD14, TLR2 and TLR4 receptors are involved in P.g-LPS effect in mouse osteoblast
Kwissa et al., Blood 2012 : In the draining lymph nodes ( LNs ), consistent with the effects in blood, all TLR-Ls induced expansion of CD14 ( + ) monocytes, but only TLR7/8-L and TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Kumar et al., PloS one 2012 (Infection...) : Moreover, stimulation of the Muller glia with TLR 2 , 3, 4, 5, 7 and 9 agonists resulted in an increased TLR expression as assayed by Western blot and flow cytometry
Lin et al., Animal 2012 (Pseudorabies) : Furthermore, higher toll-like receptor (TLR)2 and TLR9 expressions in testis were observed by PRV challenge compared with PBS groups, and higher Thr supplement attenuated PRV challenged induced the upregulation effect of TLR2 and TLR9 mRNA expression in testis ( P < 0.05 )
Wara-aswapati et al., J Periodontol 2013 : Conclusions : This study suggests that P. gingivalis infection induces TLR2 and TLR9 upregulation in patients with CP. P. gingivalis induced TLR2 expression in HGFs is partially dependent on TNF-a and may lead to sensitization of HGFs to bacterial components encountered in the periodontal microenvironment
Wang et al., PloS one 2012 (Cell Transformation, Neoplastic...) : TLR2 : TLR6 complexes mediate the effect of NF-?B inactivation by CDA-2
Feriotti et al., PloS one 2013 (Disease Susceptibility...) : Mannan or P. brasiliensis induced decreased expression of MR and TLR2 on A/J macrophages, whereas CR3, TLR4 and TLR2 were reduced on B10.A cells
Schoffelen et al., PloS one 2013 : Furthermore, we demonstrated a likely contribution of TLR4 and TLR9 , but no role for TLR2 , in the host 's cytokine response to C. gattii
Zhao et al., Fish Shellfish Immunol 2013 (Ciliophora Infections...) : TLR9 was induced in the skin and gill, whereas TLR21 was induced in the head kidney and spleen after infection