Gene interactions and pathways from curated databases and text-mining

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CYBB — IRF6

Text-mined interactions from Literome

Eklund et al., J Immunol 1999 : 1, IRF1 , and ICSBP requires either the CYBB- or NCF2 -- binding site
Muzaffar et al., Circulation 2004 (Respiratory Distress Syndrome, Adult) : LPS , TNF-alpha, and IL-1alpha all stimulated the formation of O2*- and expression of gp91(phox) in both PAVSMCs and PAECs, an effect inhibited by NADPH oxidase inhibitors, diphenyleneiodonium, and apocynin
Cassatella et al., J Biol Chem 1990 : These results suggest that induction of the gp91-phox gene and protein product by IFN-gamma or LPS is an important requirement in the mechanism of the enhancement of neutrophil and macrophage oxidative metabolism