Gene interactions and pathways from curated databases and text-mining

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EPHB2 — VWF

Text-mined interactions from Literome

Song et al., Br J Haematol 2000 : It is concluded that pVWF and thrombin induced JNK activation, but whereas thrombin induced ERK2 activation VWF did not ; functional ERK2 activity was also not required for pVWF- or thrombin dependent platelet activation
Mazharian et al., J Biol Chem 2005 (MAP Kinase Signaling System) : The ERK2 activity required for platelet adhesion was dependent on the interaction of vWF with GPIb
Garcia et al., Blood 2005 (MAP Kinase Signaling System) : VWF induced Erk2 phosphorylation and thromboxane A2 ( TXA2 ) release were completely blocked by PP2, an Src family kinase inhibitor, suggesting that Erk is downstream of Src family kinases