Gene interactions and pathways from curated databases and text-mining

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MTDH — SLC22A3

Text-mined interactions from Literome

Li et al., Cancer Sci 2011 (Breast Neoplasms...) : Taken together, our results suggest that MTDH could promote EMT in breast cancer cells in driving the progression of their aggressive behavior
Liu et al., Anticancer Drugs 2013 (Carcinoma, Non-Small-Cell Lung...) : Further results also confirmed that the expression of vimentin was decreased by the siRNA technique to directly knock down AEG-1 expression, indicating that AEG-1 was involved in UA-mediated EMT inhibition ... Altogether, UA inhibited the EMT by suppressing the expression of AEG-1 , correlating with inhibition of nuclear factor-?B in A549 cells
Wei et al., Cell Biol Int 2013 : Over-expression of AEG-1 via AEG-1 transfection elicited p38 MAPK phosphorylation and promoted EMT ... Our findings suggest that AEG-1 plays an important role in TGF-beta1 induced EMT through activation of p38 MAPK in proximal tubular epithelial cells