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MTDH — SLC22A3
Text-mined interactions from Literome
Li et al., Cancer Sci 2011
(Breast Neoplasms...) :
Taken together, our results suggest that
MTDH could
promote EMT in breast cancer cells in driving the progression of their aggressive behavior
Liu et al., Anticancer Drugs 2013
(Carcinoma, Non-Small-Cell Lung...) :
Further results also confirmed that the expression of vimentin was decreased by the siRNA technique to directly knock down AEG-1 expression, indicating that
AEG-1 was
involved in UA-mediated
EMT inhibition ... Altogether, UA
inhibited the
EMT by suppressing the expression of
AEG-1 , correlating with inhibition of nuclear factor-?B in A549 cells
Wei et al., Cell Biol Int 2013
:
Over-expression of
AEG-1 via AEG-1 transfection elicited p38 MAPK phosphorylation and
promoted EMT ... Our findings suggest that
AEG-1 plays an important role in TGF-beta1 induced
EMT through activation of p38 MAPK in proximal tubular epithelial cells