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DEFA1B — TNF

Text-mined interactions from Literome

Misuno et al., Biull Eksp Biol Med 1992 : [ Effects of human defensin HNP-1 on the production of tumor necrosis factor-alpha by human blood monocytes in vitro ]
Soehnlein et al., J Clin Invest 2008 (Disease Models, Animal...) : Mechanistically, HBP and HNP1-3 triggered macrophage release of TNF-alpha and IFN-gamma, which acted in an autocrine loop to enhance expression of CD32 and CD64 and thereby enhance phagocytosis
Riepl et al., Arthritis Res Ther 2010 (Arthritis, Rheumatoid...) : In this study, we focused on noradrenergic and TNF regulation of human neutrophil peptides 1-3 (HNP1-3) , which are proinflammatory bactericidal alpha-defensins ... TNF also inhibited HNP1-3 levels from OA but not from RA cells