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NFKB1 — NLRP2
Text-mined interactions from Literome
Shimizu et al., Immunology 2007
:
Purified N-ALP1 and
N-ALP2 from M. pneumoniae and triacylated partial synthetic lipopeptides of N-ALP1 and N-ALP2
augmented the levels of
NF-kappaB induction through TLR1- and TLR2 dependent pathways, whereas diacylated partial synthetic lipopeptides of N-ALP1 and N-ALP2 activated NF-kappaB through TLR1-, TLR2- and TLR6 dependent pathways
Fontalba et al., J Immunol 2007
:
NLRP2 , an inhibitor of the NF-kappaB pathway, is transcriptionally
activated by
NF-kappaB and exhibits a nonfunctional allelic variant ... Notably, stimulation of HEK293T cells with TNF-alpha or overexpression of the p65 subunit of
NF-kappaB resulted in up-regulation of
NLRP2 and the formation of NF-kappaB-NLRP2 promoter complexes ... Thus,
NLRP2 may
control NF-kappaB activation through a regulatory loop ... Thus,
NLRP2 may
control NF-kappaB activation through a regulatory loop