Gene interactions and pathways from curated databases and text-mining

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NFKB1 — NLRP2

Text-mined interactions from Literome

Shimizu et al., Immunology 2007 : Purified N-ALP1 and N-ALP2 from M. pneumoniae and triacylated partial synthetic lipopeptides of N-ALP1 and N-ALP2 augmented the levels of NF-kappaB induction through TLR1- and TLR2 dependent pathways, whereas diacylated partial synthetic lipopeptides of N-ALP1 and N-ALP2 activated NF-kappaB through TLR1-, TLR2- and TLR6 dependent pathways
Fontalba et al., J Immunol 2007 : NLRP2 , an inhibitor of the NF-kappaB pathway, is transcriptionally activated by NF-kappaB and exhibits a nonfunctional allelic variant ... Notably, stimulation of HEK293T cells with TNF-alpha or overexpression of the p65 subunit of NF-kappaB resulted in up-regulation of NLRP2 and the formation of NF-kappaB-NLRP2 promoter complexes ... Thus, NLRP2 may control NF-kappaB activation through a regulatory loop ... Thus, NLRP2 may control NF-kappaB activation through a regulatory loop