Gene interactions and pathways from curated databases and text-mining

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CASP1 — NTF3

Text-mined interactions from Literome

Jiang et al., Neuroscience 2005 (Diabetes Mellitus, Experimental) : Differential effect of p75 neurotrophin receptor on expression of pro-apoptotic proteins c-jun, p38 and caspase-3 in dorsal root ganglion cells after axotomy in experimental diabetes
Almeida et al., Neurobiol Dis 2009 (MAP Kinase Signaling System) : This neurotrophin prevented 3-NP induced release of cytochrome c and Smac/Diablo, caspase-3-like activity and nuclear condensation/fragmentation
Takadera et al., Biochim Biophys Acta 1998 : These results suggest that calcium ion induced apoptotic cell death was mediated by CPP32-like, but not ICE-like , protease and was regulated by a neurotrophic factor possibly, through the Map kinase cascade independent pathway