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MTA1 — RELA
Text-mined interactions from Literome
Xiao et al., J Biol Chem 2000
:
Consistently, when expressed alone, the
NRD potently
inhibits NIK mediated
NF-kappaB signaling
Law et al., Mol Cell Biol 1992
:
Neither
MTA nor mevinolin significantly
inhibited NF-kappa B activation by phorbol myristate acetate, suggesting that these agents act early in signal transduction
Minamikawa et al., J Endod 2009
:
Furthermore,
MTA caused inhibitory kappa B ( IkappaB ) phosphorylation and translocation of
nuclear factor-kappa B (NF-kappaB) subunits to nucleus
Bui-Nguyen et al., Oncogene 2010
(Carcinoma, Hepatocellular) :
NF-kappaB signaling
mediates the induction of
MTA1 by hepatitis B virus transactivator protein HBx ... Collectively, these findings revealed a previously unrecognized integral
role of
MTA1 in HBx stimulation of
NF-kappaB signaling and consequently, the expression of NF-kappaB targets gene products with functions in inflammation and tumorigenesis