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PTX3 — SELP

Text-mined interactions from Literome

Kerfoot et al., J Immunol 2004 (Encephalomyelitis, Autoimmune, Experimental) : P-selectin expression was induced by PTX , and leukocyte/endothelial interactions could be blocked with a P-selectin blocking Ab. P-selectin blockade also prevented PTX induced increase in permeability across the blood-brain barrier
Xu et al., Cell Adh Migr 2007 : Interestingly, P-selectin did not induce a detectable interleukine-8 (IL-8) secretion ( < 0.1 ng/ml ) in 30 minutes, whereas a high concentration of IL-8 ( > 50 ng/ml ) was required to increase neutrophil adhesion to Fg. P-selectin induced neutrophil adhesion was significantly inhibited by PP2 ( a Src kinase inhibitor ), but not by pertussis toxin ( PTX ; a GPCR inhibitor )