Gene interactions and pathways from curated databases and text-mining

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APC — CCND1

Text-mined interactions from Literome

Shtutman et al., Proc Natl Acad Sci U S A 1999 (Colonic Neoplasms) : Inhibitors of beta-catenin activation, wild-type adenomatous polyposis coli , axin, and the cytoplasmic tail of cadherin suppressed cyclin D1 promoter activity in colon cancer cells
Ryo et al., J Cell Sci 2003 (Neoplasms) : Pin1 regulates the expression of cyclin D1 by cooperating with Ras signaling and inhibiting the interaction of beta-catenin with the tumor suppressor APC and also directly stabilizing cyclin D1 protein
Juhlin et al., Int J Oncol 2009 (Adenoma...) : The loss of APC and GSK3-beta did not lead to augmentation of the Wnt target protein cyclin D1 or the Wnt oncoprotein beta-catenin