Gene interactions and pathways from curated databases and text-mining

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CCL20 — SAA1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Sandri et al., Immunol Lett 2008 : Herein we demonstrate that SAA induces the expression and release of CCL20 from cultured human blood mononuclear cells
Migita et al., Rheumatology (Oxford) 2009 (Arthritis, Rheumatoid) : To study the contribution of SAA to the recruitment of Th17 cells, we investigated the effects of SAA on CCL20 production by RA synoviotytes ... SAA is a most potent inducer of CCL20 secretion in RA synoviocytes compared with other inflammatory cytokines ( IL-1beta, TNF-alpha and IL-17A ) ... SAA stimulation induced CCL20 mRNA expression in RA synoviocytes, which was not affected by polymyxin B pre-treatment ... SAA induced CCL20 production was down-regulated by NF-kappaB inhibition and partially by c-jun N-terminal kinase ( JNK ) inhibition ... SAA induced CCL20 production was also suppressed by dexamethasone or FK506