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HSPB3 — TP53

Text-mined interactions from Literome

Harms et al., Mol Cell Biol 2005 : Through the use of engineered deletion mutants, we found that activation domain 2 is required for induction of the proapoptotic target gene insulin-like growth factor binding protein 3 ( IGFBP3 ) by p53 and that the basic domain inhibits induction of this gene by p53
Ma et al., J Exp Clin Cancer Res 2006 (Adenocarcinoma...) : It was also found that the absence of mutant p53 affected the signal transduction of TGFbeta/BMP pathway mainly by up-regulating the expression of BMP superfamily cytokine growth differentiation factor 9 (GDF9), activin superfamily cytokine inhibin beta B (INHBB), smads target genes insulin-like growth factor binding protein 3 ( IGFBP3 ) and involucrin (IVL)
Kawasaki et al., Neoplasia (New York, N.Y.) 2007 (Adenocarcinoma...) : Insulin-like growth factor binding protein 3 ( IGFBP3 ), which is induced by wild-type p53 , regulates IGF and interacts with the TGF-beta pathway