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TNF — TRAF3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: TRAF3 → TNF (increases) Zirlik et al., Arterioscler Thromb Vasc Biol 2007*
  Evidence: Stimulation with IL-1 or TNF- induced expression of TRAF-1, -3, and -6 in ECs and SMCs, whereas neither stimulus affected the constitutive expression of TRAF-2 or -5 (Figure 1).

Text-mined interactions from Literome

Pryhuber et al., Am J Respir Cell Mol Biol 2000 (Pneumonia) : In contrast to the epithelial cells, TRAF1 was not induced by TNF-alpha in U937 cells, a human monocytic cell line, suggesting cell type-specific regulation
Caunt et al., J Biol Chem 2001 : Ras controls tumor necrosis factor receptor associated factor ( TRAF)6 dependent induction of nuclear factor-kappa b. Selective regulation through receptor signaling components
Yao et al., J Clin Invest 2009 (Bone Resorption) : TNF , but not RANKL, increased OCP expression of TNF receptor associated factor 3 (TRAF3) , an adapter protein that regulates NF-kappaB p100 levels in B cells
Min et al., J Immunol 1997 : These data suggest that TNF activates parallel TRAF-NF-kappa B and TRAF-RAC/CDC42-JNK-c-Jun/ATF2 pathways to initiate E-selectin transcription