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CD38 — CD4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CD38 — CD4 (in vitro) Dianzani et al., Eur J Immunol 1995*
• IRef Ophid Interaction: CD38 — CD4 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: CD38 — CD4 (aggregation, confirmational text mining) Dianzani et al., Eur J Immunol 1995*

Text-mined interactions from Literome

Savarino et al., FASEB J 2003 : We used mouse cell transfectants expressing human CD4 and either CD38 or other CD4 associated molecules to show that CD38 specifically inhibits gp120/CD4 binding
Cao et al., AIDS Res Hum Retroviruses 2009 (Disease Progression...) : We identified Tregs as Foxp3+CD25+CD4+ T cells and assessed the activation of CD4+ and CD8+ T cells by the expression of CD38 , HLADR, or both markers simultaneously
Lederman et al., J Infect Dis 2011 (HIV Infections) : In multivariate analyses, naive T-cell depletion, phenotypic activation ( CD38 ( + ) and HLA-DR expression ), cycling of memory CD4 ( + ) T cells, and levels of soluble CD14 ( sCD14 ) distinguished immune failure from immune success, even when adjusted for CD4 ( + ) T-cell nadir, age at treatment initiation, and other clinical indices
Merlini et al., PloS one 2012 (Atherosclerosis...) : We measured IMT ( carotid ultrasound ) ; CD4+/CD8+ T-cell activation ( CD38 , CD45R0 ), differentiation ( CD127 ), apoptosis ( CD95 ), and senescence ( CD28, CD57 ) ( flow cytometry ) ; plasma sCD14, IL-6, TNF- a, sVCAM-1, hs-CRP, anti-CMV IgG ( ELISA ) ; LPS ( LAL )