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ECM1 — SP1

Text-mined interactions from Literome

Mukhopadhyay et al., Exp Dermatol 2007 (Keloid) : Several ECM promoters are regulated by Sp1
Park et al., J Gene Med 2009 (Liver Cirrhosis) : These results indicate that targeting Sp1 can efficiently block ECM expression, and suggest that such an approach may represent an interesting therapeutic alternative towards the treatment of cirrhosis
Lake et al., Biomaterials 2013 : Results from transfection of CAT/a5-promoter plasmids, Western blot and EMSA analyses indicated that ECM/35d significantly increase expression of a5 in HCECs as a result of alteration in the expression and DNA binding of the transcription factors NFI, Sp1 , AP-1 and PAX6