Gene interactions and pathways from curated databases and text-mining

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IL10 — RPL17

Text-mined interactions from Literome

Matsuzaki et al., Proc Natl Acad Sci U S A 2010 (Ovarian Neoplasms) : Expression of LAG-3 and PD-1 on CD8 ( + ) T cells was up-regulated by IL-10 , IL-6 ( cytokines found in tumor ascites ), and tumor derived antigen presenting cells
Ma et al., Immunology 2011 (Hepatitis C, Chronic) : PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection
Kim et al., J Immunol 2011 : IL-10 increased PD-1 ligand expression on M-DC, and IL-10 stimulated M-DCs ( M-DC/IL-10 ) induced expression of PD-1 on, and apoptosis of, CD8 ( + ) T cells and phagocytosed CD8 ( + ) T cells
Gaddis et al., J Leukoc Biol 2013 (Bacteroidaceae Infections) : Up-regulation of PD-1 was partially dependent on IL-10 but independent of TLR2 or FimA