Dong et al., Mol Med Report 2013
(Drug-Induced Liver Injury) :
IBFF attenuated the D-Gal induced increases in tumor necrosis factor-a (TNF-a) , inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) mRNA and protein levels in the liver
Séguin et al., Infect Immun 1997
(Entamoebiasis) :
Native Gal-lectin ( 100 to 500 ng/ml ) stimulated TNF-alpha and inducible nitric oxide synthase (iNOS) mRNA expression in IFN-gamma primed BMM as did lipopolysaccharide ( 100 ng/ml ) ... Antilectin monoclonal antibody IG7, which recognizes a domain ( amino acids 596 to 818 ) of the TNF-alpha mRNA stimulating region of Gal-lectin, specifically inhibited TNF-alpha and iNOS mRNA induction and TNF-alpha and NO production by primed BMM in response to Gal-lectin ( 100 ng/ml )