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IL12B — MSC
Text-mined interactions from Literome
Maggini et al., PloS one 2010
:
Using mouse thioglycolate elicited peritoneal macrophages ( M ) stimulated with LPS, we found that
MSC markedly
suppressed the production of the inflammatory cytokines TNF-alpha, IL-6,
IL-12p70 and interferon-gamma while increased the production of IL-10 and IL-12p40
Liang et al., Cell Transplant 2011
(Colitis) :
In addition to the known suppressive effects on Th1-type immune responses,
hUC-MSC mediated modulation of
IL-23/IL-17 regulated inflammatory reactions also plays an important role in the amelioration of colitis